When you install the Sonarworks Reference 4 software, it will install a program for use on all audio on your system. 

This software acts as a virtual audio output device and, once installed, sets itself to be the default audio output of your system. 

Using Sonarworks through the Focusrite interface:

By default, Reference 4 will choose the internal sound card of the computer to play audio from. You can change this by using the settings menu within the program:

Then select the desired audio device: 

Note that we have seen some behaviour where toggling between the devices has allowed audio to start working through a device. 

Disabling the Systemwide software on startup:

This section covers how to stop the software from launching with your computer, so you won't need to change the default device on boot. 

Mac:

Click the Apple symbol in the top left, go to System Preferences, and then go to Users and Groups:

Then click on your account and go to your Login Items, select Reference 4 and click the Minus button to remove it:

PC:

Right-click the Windows Start Icon in the bottom left, go to Task Manager and clock more details:

Then go to Startup, select Sonarworks and click Disable:

You'll see it then disabled: