The RedNet PCIe card does not interact directly with Pro Tools HD/HDX/HD Native rigs, though it will give you a maximum of 64 inputs and 64 outputs to/from Pro Tools with very low latency.

RedNet 5 and RedNet HD32R are designed for direct connection to Pro Tools HD/HDX/HD Native rigs over DigiLink/Mini DigiLink. Each RedNet 5/HD32R provides 32 inputs and 32 outputs to/from Pro Tools with very low latency, and multiple RedNet 5/HD32Rs can be used at the same time to increase the channel count.

The Red Range of interfaces (Red 4Pre/8Pre/8Lin/16Line) is also designed for direct connection to Pro Tools HD/HDX/HD Native rigs over DigiLink/Mini DigiLink. Each Red provides 64 inputs and 64 outputs to/from Pro Tools with very low latency, and multiple RedNet 5/HD32Rs can be used at the same time to increase the channel count in HDX2 or HDX3 rigs.